Remote Ischemic Preconditioning and Renoprotection: From Myth to a Novel Therapeutic Option?
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چکیده
منابع مشابه
Remote ischemic preconditioning and renoprotection: from myth to a novel therapeutic option?
There is currently no effective prophylactic regimen available to prevent contrast-induced AKI (CI-AKI), a frequent and life-threatening complication after cardiac catheterization. Therefore, novel treatment strategies are required to decrease CI-AKI incidence and to improve clinical outcomes in these patients. Remote ischemic preconditioning (rIPC), defined as transient brief episodes of ische...
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Objective: Remote Ischemic Preconditioning (RIPC) as the transient ischemia and reperfusion of the arm is a promising method for protecting different tissue from future ischemia. These effects might be mediated through vascular and endothelial growth factor (VEGF) pathway. We investigated the influence of RIPC on diabetic macular edema (DME) as a chronic ischemic condition in patients who were ...
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INTRODUCTION This study reports a novel strategy for investigating the key factors responsible for the protective effect of remote ischemic preconditioning (RIPC) against renal ischemia-reperfusion (IR) injury, which remains the leading cause of the acute kidney injury that increase the morbidity and mortality in patients with renal impairment. METHODS The renal blood flow of the right kidney...
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Ischemic Preconditioning Ischemic preconditioning is a widely accepted concept, first introduced in 1986 by Murray et al,1 who showed in an animal experiment that multiple brief periods (5 min) of coronary artery occlusion dramatically reduced infarct size because of the subsequent sustained coronary occlusion. Numerous reports have followed and supported the concept. The mechanism of ischemic ...
متن کاملMyocardial remote ischemic preconditioning: from pathophysiology to clinical application.
Short periods of myocardial ischemia followed by reperfusion induce a cardioprotective mechanism when the myocardium is subsequently subjected to a prolonged period of ischemia, a phenomenon known as ischemic preconditioning. As well as its application in the myocardium, ischemic preconditioning can also be induced by brief interruptions of blood flow to other organs, particularly skeletal musc...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2013
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.2013070708